By H. A. Baldwin, K. T. Britton, G. F. Koob (auth.), Dr. Detlev Ganten M.D., Ph. D., Dr. Donald Pfaff Ph. D. (eds.)
Latest factor within the present themes IN NEUROENDOCRINOLOGY se- ries which has been gaining loads of popularity as a first-rate resource for experiences in neuroendocrinology and comparable components some time past few years.
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Additional info for Behavioral Aspects of Neuroendocrinology
1986). Inhibition of OT release has been observed in the presence of relaxin (Summerlee et al. 1984; Jones and Summerlee 36 W. K. 1. Mogg 1986 and 1987; Dayanithi et al. 1987), PRL (Carter and Lightman 1987), p.. adrenergics (Moos and Richard 1979), dopamine (Seybold et al. 1976), serotonin (Mizuno et al. 1967), and the opioid peptides (Clarke et al. 1979; Summy-Long et al. 1984; Bicknell et al. 1985; Samson et al. 1985; Lincoln and Russell 1986). Recent demonstrations of the OT-stimulatory effect of the opiate antagonist naloxone (Samson et al.
All other stimuli employed, however, indicate either a clear stimulatory effect or selective release only into the portal vessels, probably indicating a more physiologic release pattern. The various stress paradigms can be roughly categorized as psychogenic, environmental, or reflexive in nature, although a clear distinction between paradigms cannot always be drawn. Psychogenic, or anticipatory, stress includes restraint (Lang et al. 1983; Gibbs 1984b; Samson et al. 1985) and tail hanging (Gibbs 1985a) or swimming (Lang et al.
Importantly, the peripheral actions of CRF on regional blood flow are completely prevented by concomitant intravenous administration of a-helical CRF9 _ 41 • Ganglionic blockade abolishes the effects of iCY administration of CRF on mesenteric vascular resistance while increases of iliac blood flow are still evident after such treatment (Overton and Fisher 1989a); it is likely that local metabolic mechanisms contribute to the increased iliac blood flow as ganglionic blockade does not prevent CRF-induced locomotor activation.
Behavioral Aspects of Neuroendocrinology by H. A. Baldwin, K. T. Britton, G. F. Koob (auth.), Dr. Detlev Ganten M.D., Ph. D., Dr. Donald Pfaff Ph. D. (eds.)