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New PDF release: Aging Research - Methodological Issues

By Carmen García-Peña, Luis Miguel Gutiérrez-Robledo, Mario Ulises Pérez-Zepeda

ISBN-10: 3319183222

ISBN-13: 9783319183220

ISBN-10: 3319183230

ISBN-13: 9783319183237

This ebook reports classical epidemiological and medical study experiences, with a spotlight on getting older. Chapters disguise methodological issues just like the clinical approach, ethics, and the results of convinced exclusion standards and the paintings contains a examine medical options like multi morbidity, frailty and performance. The authors show the problems and demanding situations for researchers of age and getting older, and likewise give some thought to the interpretation of medical wisdom, from simple to scientific and from medical to public regulations of social and healthiness care.

The specialize in getting older is what provides this publication its beneficial point of view on learn method. All authors have substantial adventure in getting older, geriatrics or gerontology and every bankruptcy contains either a theoretical framework and useful examples of stories in getting older. Readers will observe examine designs which are reviewed for uncomplicated constitution, major flaws and merits and are analyzed for particular stipulations and variables relating to aging.

This textual content is suited for either health and wellbeing care pros taking good care of older adults and researchers who're new to investigate in getting older. it truly is appropriate around the disciplines, together with drugs, psychology, social sciences and dentistry and it helps studying with graphs and figures.

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In: Hempel JE, Williams CH, Hong C (eds) Chemical biology. Methods and protocols. Methods in molecular biology. Springer Protocols, Humana Press, London, pp 93–101 25. Picazo C, Orozco H, Matallana E, Aranda A (2015) Interplay among Gcn5, Sch9 and mitochondria during chronological aging of wine yeast is dependent on growth conditions. PLoS One 10(2), e0117267. 0117267 26. Kaeberlein M, McVey M, Guarente L (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms.

The current scientific paradigm is characterized by reductionism and high specialization, which tend to focus on individual factors and lose sight of the context and interactions among factors that cross the borders of individual disciplines [18–20] (Fig. 8). There are many efforts to break free from the different limitations of the prevailing paradigm: multi-, interand transdiscipline try to integrate different scientific disciplines and make them interact [21]; data mining investigates patterns in huge quantities of crude data and translates the generated knowledge into predictive models that can be used in decision-making [22, 23]; network theory describes the interactions among elements or factors of a set [24]; time series statistics analyzes the temporal evolution of a specific observable [25], etc.

Bonnett BN, Egenvall A (2010) Age patterns of disease and death in insured Swedish dogs, cats and horses. J Comp Pathol 142(Suppl 1):S33–S38. 008 56. Roth GS, Mattison JA, Ottinger MA, Chachich ME, Lane MA, Ingram DK (2004) Aging in rhesus monkeys: relevance to human health interventions. Science 305(5689):1423–1426. 1102541 57. de Magalhaes JP (2014) Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research.

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Aging Research - Methodological Issues by Carmen García-Peña, Luis Miguel Gutiérrez-Robledo, Mario Ulises Pérez-Zepeda

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