By Alan Peters, Deborah W. Vaughan (auth.), John E. Johnson Jr. (eds.)
Approaching any activity on getting older brings a flood of pictures which are a private repetition of what has been one of many maximum and such a lot power issues of mankind. Even proscribing time to the earlier decade or so and imminent merely the biomedical sciences, one nonetheless encounters a flood of knowledge during this particularly younger learn sector. The ories and ideas abound as if every one researcher offers certainly one of his personal. this could good be anticipated; getting older is an incredibly complex sequence of crossroads related to trails or even superhighways. each one professional has a peephole (society, physique, organ, tissue, phone, or-especially in smooth biology-cellular organelles, macromolecules, or even molecules) and the perspectives of the crossroads are patently varied. therefore, the num ber of observations with regards to equals the variety of self reliant principles recommend. it's ordinary to hunt from hugely really expert wisdom a primary comprehend ing of getting older throughout the glossy learn tendencies in biology that concentrate on occasions on the mobile, subcellular, macromolecular, and molecular degrees. the last word clues needs to lie there-with one critical hassle: there are various mobilephone varieties in any physique and every mobilephone style is a truly complicated computer of its personal. also, there are capability repercussions in that assorted cells, tissues, or even molecules affect each other. this can be certainly a complicated state of affairs, and one for which we needs to search trustworthy solutions, only if we will be able to take a step again and supply a generalized view.
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Extra info for Aging and Cell Structure: Volume 1
Neurochir. 75:261-270. Cragg, B. , 1975, The density of synapses and neurons in normal, mentally defective and ageing human brains, Brain 98:81-90. , 1955, De la nature des formations argentophiles des plexus choroides (note preliminaire), Acta Neurol. Belg. 55:282-283. , 1967, Cytophotometric analysis of DNA content of rat nuclei in aging, J. Gerontol. 22:445448. , 1977, A new procedure for examining Golgi impregnated neurons by light and electron microscopy, J. Neurocytol. 6:311-337. Feldman, M.
On the other hand, the relative volume occupied by other cytoplasmic organelles such as multivesicular bodies, mitochondria, and the Golgi apparatus remains essentially constant throughout life (Fig. 11). A similar decrease in the cytoplasmic space occupied by ground substance has been found by Hinds and McNelly (1979) in the mitral cells of the olfactory bulb. However, in these neurons the volume fraction occupied by the RER remains constant, although in terms of the changes within individual cells the total volume of RER increases until 27 months of age, because the volumes of the mitral cells are also increasing during this period of time.
Therefore, it must be kept in mind that regressive changes in the aged do not necessarily reflect biological aging. 2. The Aging Sensory Unit Psychophysical tests show a progressive deterioration of somatosensory function with increasing adult age. , 1972b) (Fig. 1). A o FEMALE 8 co 7 . • co !! ) z u::: 5 ••0 0 0 • • •• 0 0 •• 0 0 0 • •• • • • • • 0 • • • 0 E • • • • MALE 0 • •• 0 • • • 0 0 0 0 0 0 0 0 o. o 0 0 • • 0 0 0 0 0 0 • 0 0 0 0 0 4 CD 5 20 40 AGE 60 IN 80 YEARS Figure 1. Touch-pressure threshold, in log, (mg), of left index finger of healthy persons.
Aging and Cell Structure: Volume 1 by Alan Peters, Deborah W. Vaughan (auth.), John E. Johnson Jr. (eds.)