By Osamu Hayaishi
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Extra info for ADP-Ribosylation Reactions. Biology and Medicine
And Haugli, F. B. (1980). J. Cell. Phys. 102, 379-384. , Stanley, S. , and Watkins, P. A. (1980). J. Biol. Chem. 255, 5838-5840. , and Schuber, F. (1980). Eur. J. Biochem. 104, 489-500. , and Hayaishi, O. (1963). Biochem. Biophys. Res. Commun. 13, 285-290. , and Dietrich, L. S. (1973). J. Biol. Chem. 248, 3500-3505. , and Hayaishi, O. (1971a). Methods Enzy mol. 18B, 141-144. , and Hayaishi, O. (1971b). Methods Enzy mol. 18B, 162-175. Olivera, B . , and Lehman, I. R. (1967). Proc. Natl. Acad. Sci.
Manlapaz-Fernandez, P . , and Olivera, Β. M. (1973). J. Biol. Chem. 248, 5150-5155. 40 Baldomero Μ. Olivera and Ari M. , Olivera, Β. , and Haugli, F. B. (1980). J. Cell. Phys. 102, 379-384. , Stanley, S. , and Watkins, P. A. (1980). J. Biol. Chem. 255, 5838-5840. , and Schuber, F. (1980). Eur. J. Biochem. 104, 489-500. , and Hayaishi, O. (1963). Biochem. Biophys. Res. Commun. 13, 285-290. , and Dietrich, L. S. (1973). J. Biol. Chem. 248, 3500-3505. , and Hayaishi, O. (1971a). Methods Enzy mol. 18B, 141-144.
D. Species Differences in NAD Metabolism The biosynthetic pathways described above for rodent tissues may not apply to all vertebrate, nor even all mammalian cell lines. Some differences between human and rodent pyridine nucleotide metabolism have been uncovered. 29 2. Pyridine Nucleotide Metabolism and ADP-Ribosylation Dietrich and Muniz (1970) studied NmPRTase from several different human tissues, and found the K for nicotinamide to be very high. 1 M, but in the presence of ATP the K for nicotinamide decreases five orders of magnitude to 1 μΜ (Dietrich and Muniz, 1972).
ADP-Ribosylation Reactions. Biology and Medicine by Osamu Hayaishi